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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
10.61
Human Site:
S6
Identified Species:
19.44
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
S6
_
_
M
Q
R
A
D
S
E
Q
P
S
K
R
P
Chimpanzee
Pan troglodytes
XP_514624
382
43769
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
S108
V
A
M
Q
Q
A
D
S
D
Q
P
S
K
R
P
Dog
Lupus familis
XP_542986
665
76981
S44
V
A
M
Q
G
A
D
S
D
Q
P
F
K
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
L6
_
_
M
Q
S
A
P
L
E
Q
P
A
K
R
P
Rat
Rattus norvegicus
XP_230789
677
77635
S66
V
A
M
Q
R
P
D
S
E
Q
P
A
K
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
G9
G
S
P
A
A
G
W
G
A
A
P
A
K
R
A
Frog
Xenopus laevis
Q6INN8
632
72730
G6
_
_
M
K
G
I
N
G
A
K
R
V
R
H
D
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
P8
M
E
N
R
I
K
R
P
R
V
D
G
E
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
P6
_
_
M
D
S
G
Q
P
W
F
P
K
I
H
T
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
M9
S
D
A
V
E
S
S
M
E
Q
H
D
S
S
D
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
0
73.3
66.6
N.A.
69.2
66.6
N.A.
N.A.
20
7.6
0
N.A.
N.A.
N.A.
15.3
13.3
P-Site Similarity:
100
0
86.6
73.3
N.A.
76.9
73.3
N.A.
N.A.
33.3
38.4
13.3
N.A.
N.A.
N.A.
15.3
20
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
8
8
31
0
0
16
8
0
24
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
8
0
0
31
0
16
0
8
8
0
0
16
% D
% Glu:
0
8
0
0
8
0
0
0
31
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
8
0
0
0
16
16
0
16
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
8
0
0
0
8
0
8
47
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
8
0
54
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
8
16
0
0
54
0
0
0
31
% P
% Gln:
0
0
0
39
8
0
8
0
0
47
0
0
0
0
0
% Q
% Arg:
0
0
0
8
16
0
8
0
8
0
8
0
8
47
0
% R
% Ser:
8
8
0
0
16
8
8
31
0
0
0
16
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
24
0
0
8
0
0
0
0
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
31
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% _